Thursday, March 17, 2011

Come speak at the BioBytes seminar!


The BioBytes seminar series is looking for TIFR researchers (faculty, post-docs, graduate students, scientists, visitors, research fellows, interns) who will volunteer to speak on topics at the intersection of biology and computer science.

Do you have ideas  you wish to communicate beyond your department? Are you able to convey insights without requiring the audience to know too much technical language? You could be a biologist looking to find 
theory collaborators, a computer scientist with thoughts on how to work with large systems, or a mathematician or physicist with a novel way of thinking about aspects of biology. If that sounds like you, then do write to me at manojg at tifr dot res dot in.

The talks are typically fairly informal blackboard talks, at the pace of a classroom lecture rather than a formal seminar. The audience is a mixed crowd consisting of computer scientists, biologists, and an occasional mathematician and physicist. The seminars are held on Thursdays, from 2 pm to 3 pm, in the STCS seminar room A 212. The seminar is usually followed by a five minute break, after which there is a discussion among those who choose to stay back.

Some possible topics for talks:
1. Systems biology
2. Immunology, epidemiology
3. The brain and cognition
4. Computer security, ideas in distributed computing
5. Evolutionary biology
6. Origin of life, self-assembly, crystallography
7. Bioinformatics and computational biology
8. -omics platforms
9. Quantum phenomena in biological systems
10. Molecular and cellular biology: protein folding, mitochondria, ribosomes, polymerases, gene regulation mechanisms, signalling pathways, cellular transport, methods and devices.
11. Vision, speech, motion planning, machine learning, ...
12. Nanoscience and nanotechnology
...

Thursday, March 10, 2011

References for "Ratchets, Pawls, and Maxwell's Demon"

Here are links to some references for this week's talk on "Ratchets, Pawls, and Maxwell's Demon."

1.The Wikipedia page on Maxwell's demon has excerpts from Maxwell's original letter.
2. Smoluchowski's analysis of the ratchet and pawl is described by Feynman in his Lectures on Physics, chapter 46.
3. Magnasco and Stolovitzky on Feynman's ratchet and pawl: http://asterion.rockefeller.edu/marcelo/Reprints/17feynmansr.pdf
4. Jarzinsky and Mazonka on an exactly solvable ratchet-pawl model: http://pre.aps.org/pdf/PRE/v59/i6/p6448_1
6. Landauer's paper: http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.68.7646&rep=rep1&type=pdf
7. Bennett on Demons, Engines and the Second Law: https://ecee.colorado.edu/~ecen4555/SourceMaterial/DemonsEnginesAndSecondLaw87.pdf . This paper also contains a description of an apparatus which according to Bennett performs the measurement/ copying operation for arbitrarily little energy.


Monday, March 7, 2011

Ratchets, pawls, and Maxwell's demon

Venue: A 212 (STCS seminar room)

Date and Time: Thursday, March 10, 2:00 pm



Abstract: I will describe Maxwell's demon, the Smoluchowski ratchet and pawl, the Szilard engine that relates information and heat, and some work of Brillouin, Landauer, Bennett and others on these topics. These topics lie at the intersection of thermodynamics and information and computer science, and I will aim to bring out this connection. On the biology side, it has been suggested that the molecular motors dynein and kinesin can be modeled as "flashing ratchets."


Prerequisites: Not strictly necessary, but it will help to know a little about random variables, Shannon entropy, and the ideal gas law.

Friday, March 4, 2011

Network Theory

Over at Network Theory (Part 1) « Azimuth, John Baez expresses a wish for "green mathematics": "a branch of mathematics... that would interact with biology and ecology just as fruitfully as traditional mathematics interacts with physics." Do take a look!

Tuesday, March 1, 2011

Classical Mechanics

Venue: A 212 (STCS seminar room)

Date and Time: Thursday, March 3, 2:00 pm


Abstract: This will be a one hour crash course on some of the basic ideas of classical mechanics: configuration space, Lagrangians, the principle of stationary action, and Noether's theorem. A reference is the online book http://math.ucr.edu/home/baez/classical/texfiles/2005/book/classical.pdf . In the discussion after the talk, we will work out some JEE physics-style mechanics problems. You are also invited to bring your own favorite mechanics problems.

The importance of classical mechanics is hard to exaggerate. It forms the basis of all of modern physics, and has inspired many deep ideas in mathematics, from manifolds and topology, to Lie groups and representation theory, to symplectic and Kahler geometry. Classical mechanics is also of obvious importance for understanding most physical phenomena, including most biological phenomena. This talk will not develop any of these connections.

Prerequisites: High school-level mathematics and physics, including integration by parts, should suffice.